Network Medicine Laboratory

Name:                Subhajit Dutta

Designation:    PhD Research Scholar

Contact No:     +91-9674499791

Email:                sd.20bt1110@phd.nitdgp.ac.in   

Skills

(1)Network Medicine, (2) R programming, (3) Drug repositioning, (4) Animal cell culture including stem cells and human cell lines, (5) RT-PCR, (6) Molecular cloning techniques, (7) UV-Vis Spectrophotometry, (8) Ultracentrifugation (9) Chromatographic techniques: Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC), (10) Plant Tissue Culture techniques: culture and sub-culture of both herbaceous & tree species, (11) Phytochemistry and Natural products (12) Heavy metal and plant chromosomal abnormalities, (13) Bioinformatics.

Research Interest

My research interests lies in the area of Stem Cell  Systems Biology, Cellular trans- differentiation, Obesity & Metabolic disorders, Network Medicine, Drug Repurposing.

Presently, I am working in two broad areas:

(1) Drug discovery associated with Obesity and type II diabetes using Network Medicine based approach, and

(2) Small molecule induced reprogramming of non-adipocyte cells to brown adipocytes for its potential use as anti-obesity drugs. Besides these, I am also involved in drug discovery associated to Polycystic Ovary Syndrome (PCOS) using the Network Medicine approach.

Publications

Journals
1. Indu K Murthy, Subhajit Dutta, Vinisha Varghese, Priya P. Joshi & Poornima Kumar. Impact of Agroforestry Systems on Ecological and Socio-Economic Systems: A Review, Global Journal of Science Frontier Research: H Environment & Earth Science. 2017. 16(5), 15-27.
https://journalofscience.org/index.php/GJSFR/article/view/1934

2. Subhajit Dutta, Mehali Mitra, Puja Agarwal, Kalyan Mahapatra, Sayanti De, Upasana Sett & Sujit Roy. Oxidative and genotoxic damages in response to heavy metal stress and maintenance of genome stability. Plant Signaling & Behavior. 2018. 13(8), 1-49.
http://dx.doi.org/10.1080/15592324.2018.1460048

3. Subhajit Dutta & Marco A. Delpiano. Neuroprotective natural products: promising candidates against neurodegenerative diseases. Bol Latinoam Caribe Plant Med Aromat. 2020. 19(5): 466 – 481.
https://doi.org/10.37360/blacpma.20.19.5.31

4. Subhajit Dutta, Raju R Wadekar & Tilottama Roy. Radioprotective natural products as alternative complements in oncological radiotherapy. Bol Latinoam Caribe Plant Med Aromat. 2021. 20(2): 101-122. https://doi.org/10.37360/blacpma.21.20.2.9

5. Subhajit Dutta, Shweta Jha: Advancement of Plant Proteomics in Biotic Stress
Responses. Journal of Plant Growth Regulation. 2021 (under revision).